Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants
Abstract While first-generation, spike (S)-based COVID-19 vaccines were effective against early SARS-CoV-2 strains, the rapid evolution of novel Omicron subvariants have substantially reduced vaccine efficacy.As such, broadly protective vaccines against SARS-CoV-2 are needed to prevent future viral emergence.In addition, it remains less socksmith s